The Metabolism Disease Database

Metabolism Disease Database

A database of curated links between metabolism and disease

To accompany the text:

Zielinski DC et. al. Nat Commun. 2015 Jun 9;6:7101.

This database is currently for academic use only.


About the database



Computational predictions of metabolic pathways perturbed in disease, based on analysis of gene expression of drug-treated cell lines in culture

Disease-linked Drug-Changed (DISLoDGED) Pathways


Curated associations between metabolism and disease in the literature

Nutrient-Disease Interactions (Set 1)
Detailed Nutrient-Disease Interactions (Set 2)
Metabolic Associations with Physiological Systems
Therapeutic Nutrient Supplements (extracted from Set 1)


Components contained within the database

Side effects
Metabolic Pathway Inhibitors




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