Bernhard Palsson, Ph.D. Principal Investigator

Director/Principal Investigator

Bernhard Palsson is the Galletti Professor of Bioengineering, Professor of Pediatrics, and the Principal Investigator of the Systems Biology Research Group in the Department of Bioengineering at the University of California, San Diego. Dr. Palsson has co-authored more than 380 peer-reviewed research articles and has authored three textbooks, with one more in preparation.

His research includes the development of methods to analyze metabolic dynamics (flux-balance analysis, and modal analysis), and the formulation of complete models of selected cells (the red blood cell, E. coli, hybridoma, and several human pathogens).

He sits on the editorial broad of several leading peer-reviewed microbiology, bioengineering, and biotechnology journals. He previously held a faculty position at the University of Michigan for 11 years and was named the G.G. Brown Associate Professor at Michigan in 1989, a Fulbright fellow in 1995, and an Ib Henriksen Fellow in 1996.

He is the author of 40 U.S. patents, the co-founder of several biotechnology companies, and holds several major biotechnology awards. He received his PhD in Chemical Engineering from the University of Wisconsin, Madison in 1984. Dr. Palsson is a member of the National Academy of Engineering and is a Fellow of both the AAAS and the AAM.

Publications

Patents

Editorial Activities

Technology Transfer

Patents

Bernhard Ø. Palsson, Ph.D

U.S. Patent No. 5,399,493. Methods and compositions for the optimization of human hematopoietic progenitor cell cultures

U.S. Patent No. 5,437,994. Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells

U.S. Patent No. 5,459,069. Device for maintaining and growing human stem and/or hematopoietics cells

U.S. Patent No. 5,534,423. Methods of increasing rates of infection by directing motion of vectors

U.S. Patent No. 5,605,822. Methods, compositions and devices for growing human hematopoietic cells

U.S. Patent No. 5,614,378. Photobioreactors and closed ecological life support systems and artificial lungs containing the same

U.S. Patent No. 5,616,487. Stabilized retrovirus composition

U.S. Patent No. 5,635,386. Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture

U.S. Patent No. 5,646,043. Methods for the ex vivo replication of human stem cells and/or expansion of human progenitor cells

U.S. Patent No. 5,654,185. Methods, compositions and apparatus for cell transfection

U.S. Patent No. 5,670,147. Compositions containing cultured mitotic human stem cell

U.S. Patent No. 5,670,351. Methods and compositions for the ex vivo replication of human hematopoietic stem cells

U.S. Patent No. 5,672,494. Methods of increasing rates of infection by directing motion of vectors

U.S. Patent No. 5,688,687. Bioreactor for mammalian cell growth and maintenance

U.S. Patent No. 5,763,266. Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells

U.S. Patent No. 5,804,431. Method, compositions and apparatus for cell transfection

U.S. Patent No. 5,811,274. Methods, compositions and apparatus for cell transfection

U.S. Patent No. 5,866,400. Methods of increasing rates of infection by directing motion of vectors

U.S. Patent No. 5,874,266. Targeted system for removing tumor cells from cell populations

U.S. Patent No. 5,888,807. Devices for maintaining and growing human stem and/or hematopoietics cells

U.S. Patent No. 6,326,198. Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells

U.S. Patent No. 6,514,722. Method and apparatus for selectively targeting specific cells within a cell population

U.S. Patent No. 6,524,797. Methods of identifying therapeutic compounds in a genetically defined setting

U.S. Patent No. 6,534,308. Method and apparatus for selectively targeting specific cells within a mixed cell population

U.S. Patent No. 6,642,018. Method for inducing response in one or more targeted cells

U.S. Patent No. 6,667,034. Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture, methods for assaying the effect of substances on lineage-specific cell production, and cell compositions produced by these cultures

U.S. Patent No. 6,753,161. Optoinjection methods

U.S. Patent No. 6,804,385. Method and device for selectively targeting cells within a three-dimensional specimen

U.S. Patent No. 7,092,557. Method and device for selectively targeting cells within a three-dimensional specimen

U.S. Patent No. 7,127,379. Method for the evolutionary design of biochemical reaction networks

U.S. Patent No. 7,129,070. Targeted system for removing tumor cells from cell populations

U.S. Patent No. 7,300,795. Optoinjection methods

U.S. Patent No. 7,374,880. Methods of identifying therapeutic compounds in a genetically defined setting

U.S. Patent No. 7,505,618. Method and apparatus for selectively targeting specific cells within a cell population

U.S. Patent No. 7,734,420. Methods and systems to identify operational reaction pathways

U.S. Patent No. 7,751,981. Articles of manufacture and methods for modeling Saccharomyces cerevisiae metabolism

U.S. Patent No. 7,869,957. Methods and systems to identify operational reaction pathways

U.S. Patent No. 7,920,993 B2. Method for the evolutionary design of biochemical reaction networks

U.S. Patent No. 7,920,994 B2. Method for the evolutionary design of biochemical reaction networks

U.S. Patent No. 8,301,393 B2. Methods and systems for genome-scale kinetic modeling

Canada Patent No. 2,500,761. Methods and systems to identify operational reaction pathways

U.S. Patent No. 8,606,553. Methods for identifying drug targets based on genomic sequence data

top

Technology Transfer

Bernhard Ø. Palsson, Ph.D.

Genomatica

Aastrom Biosciences

Iceland Genomics Corporation

top

Contact Information

Email Address palsson@ucsd.edu

Mailing Address 9500 Gilman Drive Mail Code 0412 La Jolla, CA 92093-0412

Location

Location

417 Powell-Focht Bioengineering Hall

9500 Gilman Drive La Jolla, CA 92093-0412

Contact Us

Contact Us

In Silico Lab:  858-822-1144

Wet Lab:  858-246-1625

FAX:   858-822-3120

Website Concerns: sbrgit@ucsd.edu

User Login